A Secret Weapon For ceesdekker.net
A Secret Weapon For ceesdekker.net
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Human Rad51 filaments on double- and one-stranded DNA: correlating normal and irregular varieties with recombination function.
Back again in 1991, Sumio Iijima on the NEC Company experienced described the synthesis of carbon nanotubes. Band framework calculations instructed that these nanotubes could show metallic band conduction. This may be a big gain around the conducting polymers we experienced explored, which ended up, in truth, disordered semiconductors featuring basically variable-vary hopping conductivity.
2007, initially actual-time detection of strand Trade in homologous recombination by RecA; discovery of a minimal persistence duration of finishes of microtubules; and resolved the mechanism of biosensing with carbon nanotubes
Dekker is naast zijn wetenschappelijk werk ook bekend vanwege zijn belangstelling voor de relatie tussen geloof en wetenschap en de discussie rond intelligent design in 2005. (nl)
SMC complexes can pass Actual physical roadblocks larger than their ring dimensions, indicating a nontopological mechanism for DNA loop extrusion
All parameters ended up exactly the same for each panel In this particular movie, aside from the Original placement of the 6hb rod (shown in blue) within the nanopore. Simulations that terminated early resulting from translocation with the rod in the pore are marked by a gray history.
Nanopores stand for a sublime and multipurpose tool to measure one molecules. We investigate novel detection modes with good-point out nanopores and many ways to evaluate proteins with nanopores. Initiatives encompass the subsequent:
Being familiar with essential procedures regulating the spatial and dynamic organisation of your DNA in live cells.
Resolving the step dimension in condensin-driven DNA loop extrusion identifies ATP binding because the stage-producing procedure
In 1993 he was appointed as Associate Professor at Delft College of Technology. Inside the mid-nineties Dekker and his team reached achievements with the discovery in the Digital Attributes of https://www.ceesdekker.net carbon nanotubes, the very first solitary-molecule transistor together with other nanoscience.
Nature Physics many thanks the anonymous reviewers for his or her contribution for the peer evaluation of the perform.
2008, initially observation of protein-coated DNA translocation by nanopores; solved the origin with the electrophoretic pressure on DNA in nanopores; uncovered a major velocity raise of microtubules in electrical fields; identified an anomalous electro-hydrodynamic orientation of microtubules; and settled the origin of noise in carbon nanotubes in liquid
Supercoiling-dependent DNA binding: quantitative modeling and purposes to bulk and solitary-molecule experiments